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Link to the site www.programmed-aging.org

Empirical evidence about evolutionary theories on ageing
Exposition of an adaptive theory on ageing
Ageing researches timeline
Phylogeny of age-related fitness decline in the wild and of related fenomena

An interesting paper about evolutionary theories on ageing HTML PDF

G. Libertini (1983) Ragionamenti Evoluzionistici,
Società Editrice Napoletana, Napoli

G. Libertini (2011) Evolutionary Arguments on Aging, Disease, and Other Topics,
Azinet Press, Crownsville MD (USA)
Cover in the original edition Text in the Italian reprint (PDF, 698k; DOC, 678k)
Software for the figures (ZIP, 50k) Text in the English reprint (PDF, 836k; DOC 1245k)

G. Libertini (1988) An Adaptive Theory of the Increasing Mortality with Increasing Chronological Age in Populations in the Wild, J. Theor. Biol., 132, 145-162
DOC (176k) PDF (205k) PDF (from fotocopies of the original; 965k) HTM PubMed Google Scholar

G. Libertini & A. Di Donato (1992) Computer-aided gene design, Protein Engineering, 5, 821-825 (link to PubMed)

G. Libertini & A. Di Donato (1994) Reconstruction of Ancestral Sequences by the Inferential Method, a Tool for Protein Engineering Studies, Journal of Molecular evolution, 39, 219-229 (link to PubMed)

Monaldi Hospital 2005 Seminary - Part I, oral presentation in PPT format, 658k
Monaldi Hospital 2005 Seminary - Part II, oral presentation in PPT format, 958k

G. Libertini (2006) Evolutionary explanations of the “actuarial senescence in the wild” and of the “state of senility, TheScientificWorld Journal, 6, 1086-1108 DOI 10.1100/tsw.2006.209, in PDF format, 219k
Paper figures, in xls format, 160k
Two simulation programs (IMICAW.EXE and IMICAC.EXE) with source files and instructions, in zip format, 37k
Analysis of Ricklefs data, in xls format, 321k
[PubMed] [Google Scholar]

Evidenza empirica a riguardo di due ipotesi evolutive per le specie che, allo stato selvatico, mostrano un incremento della mortalità in funzione dell’età, oral presentation at SIBE after congress scientific meeting, Florence, September 8, 2006, in PPT format, 312k

G. Libertini (2008) Empirical evidence for various evolutionary hypotheses on species demonstrating increasing mortality with increasing chronological age in the wild, TheScientificWorld Journal, 8, 183-93 DOI 10.1100/tsw.2008.36, in PDF format, 199k
[PubMed] [Google Scholar]

SIBE (Italian Society of Evolutionary Biology) - 3^dh National Congress - Alghero, October 2-5, 2008
A simulation model for the evolutionary advantage of sex, oral presentation in PPT format, 781k
Simulation program, in zip format, 101k
Phylogeny of age-related fitness decline function, poster in PPT format, 329k
Evolutionary definition of disease phenomenon, poster in PPT format, 542k

G. Libertini (2009) The Role of Telomere-Telomerase System in Age-Related Fitness Decline, a Tameable Process, in Telomeres: Function, Shortening and Lengthening (ed. Leonardo Mancini), Nova Science Publishers Inc., New York (ISBN 978-1-60692-350-4), in word format, 997k

G. Libertini (2009) Prospects of a Longer Life Span beyond the Beneficial Effects of a Healthy Lifestyle, in Handbook on Longevity: Genetics, Diet & Disease (eds. Jennifer V. Bentely and Mary Ann Keller), Nova Science Publishers Inc., New York (ISBN 978-1-60741-075-1), in word format, 1860k

Moscow, MSU, Lomonosov University, Belozersky Institute, May 25-26, 2010
International Workshop "From Homo sapiens to Homo sapiens liberatus"
Program + Abstracts Participants Files in DOC format DOC
Oxidative damage and aging, oral presentation in PPT format, 796k
Arguments against telomere-telomerase system as general defence against cancer, poster in PPT format, 248k
A proposal: Project "Homo sapiens liberatus II"!, poster in PPT formato, 727k
Comparison between two paradigms about aging, poster in PPT format, 278k
Are C. elegans and D. melanogaster valid animal models for studies on aging?, poster in PPT format, 251k

SIBE (Italian Society of Evolutionary Biology) - 4^th National Congress - Milan, September 2-4, 2010
Information about the Congress
Evolutionary definition of normality, accepted as poster, in PPT format: (Part 1, 649k), (Part 2, 399k), as oral presentation, in PPT format, 936k
Reproposition for the Italian scientific world of:
Comparison between two paradigms about aging, accepted as poster, in PPT format, 278k
Are C. elegans and D. melanogaster valid animal models for studies on aging?, accepted as poster, in PPT format, 251k

G. Libertini (2011) Concordance of the Predictions of a Simulation Model for the Evolutionary Advantage of Sex with Observational Evidence WebmedCentral ZOOLOGY 2 (11):WMC002464
WebmedCentral Google Scholar

G. Libertini (2011) Phylogeny of Age-Related Fitness Decline in the Wild and of Related Phenomena. WebmedCentral AGING 2(11):WMC002530
WebmedCentral Google Scholar

G. Libertini (2011) A test about the knowledge of some concepts of Evolutionary Medicine in the medical field. WebmedCentral GENERAL MEDICINE 2(11):WMC002529
WebmedCentral Google Scholar

G. Libertini (2011) Evolutionary interpretations of Aging, Disease Phenomenon, and Sex, Copernican Editions, 7125 k
Idem (2012), Nabu Press (Reprint not authorized but tolerated, link to buy on Amazon)

G. Libertini (2012) Classification of Phenoptotic Phenomena, Biochemistry (Moscow), vol. 77, n. 7, 847-57, in PDF format, 155 k
[PubMed] [Google Scholar] [Biochemistry (Moscow)]

G. Libertini (2012) Phenoptosis, Another Specialized Neologism, or the Mark of a Widespread Revolution?, Biochemistry (Moscow), vol. 77, n. 7, 955-60, in PDF format, 82 k
[PubMed] [Google Scholar] [Biochemistry (Moscow)]

Larnaka (Cyprus), May 25, 2013 - International Symposium "Pathways to Indefinite Lifespans"
Non-Programmed versus Programmed Paradigm of Aging, oral presentation in PPT format, 1188k

SIBE (Italian Society of Evolutionary Biology) - 5^th National Congress - Trento, August 28-31, 2013
Program, abstracts, Author index (1.8 MB)
Evidence for aging theories from the study of a hunter-gatherer people (Ache of Paraguay), accepted as oral presentation, in PPT format, 2.1MB
Prevention of refractive defects of vision by means of Evolutionary Medicine, accepted as poster, in PPT format (Part 1, 0.6MB), (Part 2, 0.5MB), as oral presentation, in PPT format, 1.5MB
Malocclusions and urolithiasis in the context of Evolutionary Medicine, accepted as poster, in PPT format (Part 1, 0.8MB), (Part 2, 0.4MB), as oral presentation, in PPT format, 1.9MB

G. Libertini (2013) Evidence for aging theories from the study of a hunter-gatherer people (Ache of Paraguay), Biochemistry (Moscow), vol. 78, no. 9, 1306-17, PDF format, 155 k
[PubMed] [Google Scholar] [Biochemistry (Moscow)]

G. Libertini (2014) The Concept of Phenoptosis and its Usefulness for Controlling Aging, Current Aging Science, vol. 7, n. 1, 32-7, in formato PDF, 219 k
[PubMed] [Google Scholar]

G. Libertini (2014) The Programmed Aging Paradigm: How We Get Old, Biochemistry (Moscow), vol. 79, n. 10, 1004-16, in formato PDF, 557 k
[PubMed] [Google Scholar] [Biochemistry (Moscow)]

The International Association of Gerontology and Geriatrics (IAGG), European Region 8th Congress, Dublin, April 23-26, 2015
G. Libertini (2015) How we age according to Programmed Aging Paradigm, poster (in PPT format, 1.2 MB) / oral presentation (in PPT format, 3.1 MB)
G. Libertini (2015) Non-programmed versus Programmed Aging Paradigm, poster (in PPT format, 0.3 MB) / oral presentation (in PPT format, 4.4 MB)

G. Libertini (2015) Non-programmed Versus Programmed Aging Paradigm, Current Aging Science, vol. 8, n. 1, 55-68, in PDF format, 373 k
[PubMed] [Google Scholar]

G. Libertini (2015) Editorial: Is Aging a Failure or a Conquest of Natural Selection?, Current Aging Science, vol. 8, n. 1, 1-2, in PDF format, 749 k
[PubMed] [Google Scholar]

SIBE (Italian Society of Evolutionary Biology) - 6^th National Congress - Bologna, August 31 - September 3, 2015
Program and abstracts (in PDF format, 0.7MB)
Evolutionary classification of diseases and similar conditions, accepted as oral presentation (in PPT format, 2.4MB)
Idem, as poster (in PPT format, 0.7MB)

G. Libertini (2015) Phylogeny of Aging and Related Phenoptotic Phenomena, Biochemistry (Moscow), vol. 80, n. 12, 1529-46, in PDF format, 0.9 MB
[PubMed] [Google Scholar]

Seminario del 2 dicembre 2015 presso la Scuola di Specializzazione in Geriatria, Università di Napoli “Federico II”, Dir. Prof. Nicola Ferrara
G. Libertini, Meccanismi dell’invecchiamento secondo la tesi dell’invecchiamento programmato (Programmed Aging Paradigm), in PPT format, 4.8 MB

G. Libertini, Ferrara N. (2016) Aging of perennial cells and organ parts according to the programmed aging paradigm, Age (Dordr.), 38(2), 1-13, in PDF format, 1.1 MB
[PubMed] [Google Scholar]

G. Libertini, N. Ferrara (2016) Possible interventions to modify aging, Biochemistry (Moscow), vol. 81, n. 12, 1413-28, in PDF format, 0.8 MB
[PubMed] [Google Scholar]

G. Libertini, G. Rengo, N. Ferrara (2017) Aging and aging theories, Official Journal of the Italian Society of Gerontology and Geriatrics, vol. 65, 59-77, in PDF format, 2.0 MB
[Journal of Gerontology and Geriatrics] [Google Scholar]

G. Libertini (2017) The feasibility and necessity of a revolution in geriatric medicine, OBM Geriatrics, 1(2), doi: 10.21926/obm.geriat.1702002, in PDF format, 1.5 MB
[OBM Geriatrics] [Google]

SIBE (Italian Society of Evolutionary Biology) - 7^th National Congress - Rome, August 28-31, 2017
Programme (in PDF format, 1.3 MB)
Abstracts (in PDF format, 1.9 MB)
Allergic and autoimmune diseases in the interpretation of evolutionary medicine, oral presentation (in PPT format, 5.0 MB)

G. Libertini (2017) Programmed Aging Paradigm and Aging of Perennial Neurons, Ch. 5 in: Shamim I. Ahmad (ed.), Aging. Exploring a Complex Phenomenon, CRC Press, in PDF format, 3.2 MB [Google Scholar]

G. Libertini (2017) Sex and Aging: A Comparison between Two Phenoptotic Phenomena, Biochemistry (Moscow), vol. 82, n. 12, 1435-45, in PDF format, 1.3 MB
Supplementary materials, in a ZIP file, 2,4 MB

G. Libertini, with the collaboration and the presentation of N. Ferrara (2017) Come e perché invecchiamo: la via per una longevità illimitata, in PDF format, 12.8 MB [Google]

G. Libertini, Why and how we age: the way towards an unlimited longevity (2017), in PDF format, 16.5 MB

G. Libertini, N. Ferrara, G. Rengo and G. Corbi (2018), Elimination of Senescent Cells: Prospects According to the Subtelomere-Telomere Theory, in PDF format, 0.9 MB

The International Association of Gerontology and Geriatrics (IAGG), European Region Congress, Gothenburg, May 23-25, 2019
G. Libertini, G. Corbi, N. Ferrara (2019) The necessity of a revolution in gerontology and geriatrics, oral presentation (in PPT format, 1.8 MB)
G. Libertini, G. Corbi, N. Ferrara (2019) The necessity of a change in the interpretation and cure of Alxheimer's Disease, Parkinson's Disease and Age-related Macular Degeneration, oral presentation (in PPT format, 2.0 MB)

Entries by Libertini G. in Gu D., Dupre M. (eds) Encyclopedia of Gerontology and Population Aging. Springer, Cham (2019)

Aging and Cancer (in PDF format, 0.2M)
Aging Definition (in PDF format, 0.5M)
Aging Pathology (in PDF format, 0.3M)
Gradual Cell Senescence (in PDF format, 0.2M)
Kin Selection Aging Theory (in PDF format, 0.3M)
Non-evolutionary and Evolutionary Aging Theories (in PDF format, 0.2M)
Programmed (Adaptive) Aging Theories (in PDF format, 0.2M)
Telomere-Subtelomere-Telomerase System (in PDF format, 0.6M)

SIBE (Italian Society of Evolutionary Biology) - 8^th National Congress - Padua, September 1-4, 2019
Programme (in PDF format, 0.2 MB)
Abstracts (in PDF format, 3.0 MB)
Importance and Meaning of Phenoptosis, oral presentation (in PPT format, 2.3 MB)

G. Libertini, G. Corbi, M. Cellurale, N. Ferrara (2019), Age-related dysfunctions: Evidence and relationship with some risk factors and protective drugs, in PDF format, 0.9 MB

Moscow, MSU, Lomonosov University, Belozersky Institute, February 20-21, 2020 - 3-rd International Conference "Homo sapiens liberatus"
The core of the core of aging mechanisms, oral presentation in PPT format, 3.7 Mb

G. Libertini, G. Corbi, N. Ferrara (2020), Importance and meaning of TERRA sequences for aging mechanisms, in PDF format, 0.9 MB

G. Libertini, G. Corbi, V. Conti, O. Shubernetskaya, N. Ferrara (2021), Evolutionary Gerontology and Geriatrics, published by Springer
Cover Draft of the first Chapter (in PDF format, 2.2 MB; copyright by Springer)

G. Libertini, O. Shubernetskaya, G. Corbi, N. Ferrara (2021), Is evidence supporting the subtelomere-telomere theory of aging?, in PDF format, 0.7 MB

SIBE (Italian Society of Evolutionary Biology) - 9^th National Congress - Ancona, September 4-7, 2022
Abstracts (in PDF format, 1.6 MB)
The origin of autism spectrum disorders in the interpretation of Evolutionary Medicine, oral presentation (in PPT format, 1.5 MB)

G. Libertini, G. Corbi, O. Shubernetskaya, N. Ferrara (2022), Is Human Aging a Form of Phenoptosis?, in pdf format, 0.6 MB

G. Libertini (2022), Perspectives to modify and counter aging in the frame of subtelomere-telomere theory of aging, in PDF format, 1.1 MB

G. Libertini (2023), Phenoptosis and the Various Types of Natural Selection, in PDF format, 0.7 MB

SIBE (Italian Society of Evolutionary Biology) - 10^th National Congress - Naples, September 8-11, 2024
G. Libertini (2024), The cellular mechanism of aging from hypothesis to scientific evidence, in PPT format, 2.1 MB

Other publications (regarding topics of Local History; from the site: Istituto di Studi Atellani)

VertEolo Project

Notes for a New Physics - Second Edition with Changes and Additions (5,0 MB) Appunti per una Nuova Fisica - Seconda Edizione con Modifiche e Aggiunte (5,2 MB)